Neurostimulation for Advanced Parkinson Disease and Quality of Life at 5 Years (JAMA Network Open)

By JAMA Network Open; Jan 18, 2024About The Study: This nonrandomized controlled trial of 108 patients with advanced Parkinson disease found that at 5-year follow-up quality of life remained stable in the deep brain stimulation of the subthalamic nucleus (STN-DBS) group and worsened in the standard-of-care medication group, mainly driven by the favorable effect of STN-DBS on mobility. These findings may provide helpful information when counseling patients on the efficacy of STN-DBS for Parkinson disease and monitoring patients postoperatively in long-term follow-up.Authors: Stefanie T. Jost, Ph.D., and Haidar S. Dafsari, M.D., of the University of Cologne, Germany, are the corresponding authors.  (doi:10.1001/jamanetworkopen.2023.52177)Citation

  • Jost ST, Aloui S, Evans J, et al. Neurostimulation for Advanced Parkinson Disease and Quality of Life at 5 Years: A Nonrandomized Controlled Trial. JAMA Netw Open. 2024;7(1):e2352177. doi:10.1001/jamanetworkopen.2023.52177

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support. About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. #  #  #For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.SOURCE: EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JANUARY 18, 2024; http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.52177?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=011824

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